Efficacy & Safety

A Few Facts About Common Viruses that NIH Studied with VFI Humic Acid®


Herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) are responsible for orofacial and genital herpes, respectively.  Approximately 45 million Americans are serum-positive for genital herpes (type 2), with 20 million routinely exhibiting symptoms.  It is believed that 80% of Americans are serum-positive for orofacial herpes (type 1), virtually all of whom occasionally exhibit symptoms.  Roughly half of herpes simplex viruses are today Acyclovir-resistant.  Human cytomegalovirus (HCMV) is pervasive in the U.S.: 90% of the urban U.S. population is serum-positive for HCMV, although infection in immunocompetent individuals is generally asymptomatic.  Varicella zoster virus (VZV) is the cause of chickenpox in children and shingles in adults.  Epstein-Barr virus (EBV) is the cause of infectious mononucleosis in adolescents and young adults.


Influenza A (INFL-A) (2 strains) and B (INFL-B) (1 strain) are routinely responsible for 20,000-30,000 deaths annually in the U.S., and well over 100,000 hospitalizations.  Pandemics occur when the virus mutates radically.  The 1918 “Spanish flu” [Influenza A(H1N1)] caused approximately 500,000 deaths in the U.S. and 50,000,000-100,000,000 worldwide.  The 1957-58 “Asian flu” [influenza A(H2N2)] resulted in 70,000 deaths in the U.S., while the 1968-69 “Hong Kong flu” [influenza A(H3N2)] brought about 34,000 U.S. dead.


Pichinde virus (PICV) is a “New-World” (South American) arenavirus whose members are generally associated with rodent-transmitted disease in humans.  Punta Toro virus (PUTV) is a South American phlebovirus of the Bunyaviridae family of viruses, and is transmitted by sand flies.  Crimean-Congo, Rift Valley, and Hanta viruses are also members of this family.


In Vitro Efficacy Studies

     Click on the respective links below to access each report.
     (some files are large and may require several minutes to download)


     Inhibition of HIV Replication

University of Southern California Medical School
Southern Research Institute

     Inhibition of HSV Infection

Specialty Labs

     Broad-Spectrum Antiviral Efficacy

National Institutes of Health


In Vitro Safety Studies



In Vivo Safety Studies




Certificate of Analysis
Material Safety Data Sheet 
Raw Product Data Summary